The Effects of the Contact Activation System on Hemorrhage

The contact activation system (CAS) exerts effects on coagulation via multiple mechanisms, which modulate both the intrinsic and extrinsic coagulation cascades as well as fibrinolysis and platelet activation. While the effects of the CAS on blood coagulation measured as activated partial thromboplas...

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Bibliographic Details
Main Authors: Fabrício Simão, Edward P. Feener
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00121/full