Enterovirus 71-induced neurological disorders in young gerbils, Meriones unguiculatus: development and application of a neurological disease model.

A reliable disease model mimicking Enterovirus 71 (EV71) infection in humans is essential for understanding pathogenesis and for developing a safe and effective vaccine. Commonly used rodent models including mouse or rat models are not suitable for vaccine evaluation because the rodents are resistan...

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Main Authors: Ping-Ping Yao, Lei Qian, Yong Xia, Fang Xu, Zhang-Nv Yang, Rong-Hui Xie, Xiao Li, Wei-Feng Liang, Xiao-Xiao Huang, Zhi-Yong Zhu, Han-Ping Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528719?pdf=render