Xenoantigenicity of porcine decellularized valves

Xenoantigenicity of porcine decellularized valves

Abstract Background The xenoantigenicity of porcine bioprosthetic valves is implicated as an etiology leading to calcification and subsequent valve failure. Decellularization of porcine valves theoretically could erase the antigenicity of the tissue leading to more durable prosthetic valves, but the...

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Bibliographic Details
Main Authors: Meghana R. K. Helder, Nicholas J. Stoyles, Brandon J. Tefft, Ryan S. Hennessy, Rebecca R. C. Hennessy, Roy Dyer, Tyra Witt, Robert D. Simari, Amir Lerman
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Valve deterioration
Valve durability
Immune response
Online Access:http://link.springer.com/article/10.1186/s13019-017-0621-5

Internet

http://link.springer.com/article/10.1186/s13019-017-0621-5

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