Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex

Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex

Abstract Background Why we sleep is still one of the most perplexing mysteries in biology. Strong evidence indicates that sleep is necessary for normal brain function and that sleep need is a tightly regulated process. Surprisingly, molecular mechanisms that determine sleep need are incompletely des...

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Bibliographic Details
Main Authors: Jason R. Gerstner, John N. Koberstein, Adam J. Watson, Nikolai Zapero, Davide Risso, Terence P. Speed, Marcos G. Frank, Lucia Peixoto
Format: Article
Language:English
Published: BMC 2016-10-01
Series:BMC Genomics
Subjects:
Sleep
Sleep deprivation
Circadian
Microarray
Gene
mRNA
Online Access:http://link.springer.com/article/10.1186/s12864-016-3065-8

Internet

http://link.springer.com/article/10.1186/s12864-016-3065-8

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