Negative Effects of High Glucose Exposure in Human Gonadotropin-Releasing Hormone Neurons

Metabolic disorders are often associated with male hypogonadotropic hypogonadism, suggesting that hypothalamic defects involving GnRH neurons may impair the reproductive function. Among metabolic factors hyperglycemia has been implicated in the control of the reproductive axis at central level, both...

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Bibliographic Details
Main Authors: Annamaria Morelli, Paolo Comeglio, Erica Sarchielli, Ilaria Cellai, Linda Vignozzi, Gabriella B. Vannelli, Mario Maggi
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/684659