Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration

Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration

Abstract Microglia are brain immune cells that constantly survey their environment to maintain homeostasis. Enhanced microglial reactivity and proliferation are typical hallmarks of neurodegenerative diseases. Whether specific disease-linked microglial subsets exist during the entire course of neuro...

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Bibliographic Details
Main Authors: Tuan Leng Tay, Sagar, Jana Dautzenberg, Dominic Grün, Marco Prinz
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Acta Neuropathologica Communications
Subjects:
Microglia
Recovery
Neurodegeneration
Single-cell RNA analysis
Online Access:http://link.springer.com/article/10.1186/s40478-018-0584-3

Internet

http://link.springer.com/article/10.1186/s40478-018-0584-3

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