Ginkgolide B reduces atherogenesis and vascular inflammation in ApoE(-/-) mice.
To investigate whether ginkgolide B (a platelet-activating factor inhibitor) affects vascular inflammation in atherosclerosis-prone apolipoprotein E-deficient (ApoE(-/-)) mice.Human platelets were used to evaluate the effects of ginkgolide B on platelet aggregation and signal transduction. Ginkgolid...
Main Authors: | Xiyun Liu, Gexin Zhao, Yan Yan, Li Bao, Beidong Chen, Ruomei Qi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3359353?pdf=render |
Similar Items
-
Ginkgolide B Suppresses Intercellular Adhesion Molecule-1 Expression via Blocking Nuclear Factor-κB Activation in Human Vascular Endothelial Cells Stimulated by Oxidized Low-Density Lipoprotein
by: Rui Li, et al.
Published: (2009-01-01) -
Ginkgolide B Inhibits JAM-A, Cx43, and VE-Cadherin Expression and Reduces Monocyte Transmigration in Oxidized LDL-Stimulated Human Umbilical Vein Endothelial Cells
by: Xueqing Liu, et al.
Published: (2015-01-01) -
Ginkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 expression in oxidized LDL-stimulated human umbilical vein endothelial cells.
by: Lina Ma, et al.
Published: (2013-01-01) -
Ginkgolide B inhibits platelet and monocyte adhesion in TNFα-treated HUVECs under laminar shear stress
by: Ming Zhang, et al.
Published: (2018-07-01) -
Citreoviridin Enhances Atherogenesis in Hypercholesterolemic ApoE-Deficient Mice via Upregulating Inflammation and Endothelial Dysfunction.
by: Hai-Feng Hou, et al.
Published: (2015-01-01)