Ginkgolide B reduces atherogenesis and vascular inflammation in ApoE(-/-) mice.

To investigate whether ginkgolide B (a platelet-activating factor inhibitor) affects vascular inflammation in atherosclerosis-prone apolipoprotein E-deficient (ApoE(-/-)) mice.Human platelets were used to evaluate the effects of ginkgolide B on platelet aggregation and signal transduction. Ginkgolid...

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Bibliographic Details
Main Authors: Xiyun Liu, Gexin Zhao, Yan Yan, Li Bao, Beidong Chen, Ruomei Qi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359353?pdf=render