Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification.
Heritable, but reversible, changes in transposable element activity were first observed in maize by Barbara McClintock in the 1950s. More recently, transposon silencing has been associated with DNA methylation, histone H3 lysine-9 methylation (H3mK9), and RNA interference (RNAi). Using a genetic app...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2003-12-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC300680?pdf=render |