Effect of Hydrogen Peroxide on the Biosynthesis of Heme and Proteins: Potential Implications for the Partitioning of Glu-tRNAGlu between These Pathways

Effect of Hydrogen Peroxide on the Biosynthesis of Heme and Proteins: Potential Implications for the Partitioning of Glu-tRNAGlu between These Pathways

Glutamyl-tRNA (Glu-tRNAGlu) is the common substrate for both protein translation and heme biosynthesis via the C5 pathway. Under normal conditions, an adequate supply of this aminoacyl-tRNA is available to both pathways. However, under certain circumstances, Glu-tRNAGlu can become scarce, resultin...

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Bibliographic Details
Main Authors: Carolina Farah, Gloria Levicán, Michael Ibba, Omar Orellana
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
heme
oxidative stress
acidophilic
aminoacyl-tRNA
Online Access:http://www.mdpi.com/1422-0067/15/12/23011

Internet

http://www.mdpi.com/1422-0067/15/12/23011

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