Ophthalmic In Situ Gelling System Containing Lanosterol Nanoparticles Delays Collapse of Lens Structure in Shumiya Cataract Rats

Ophthalmic In Situ Gelling System Containing Lanosterol Nanoparticles Delays Collapse of Lens Structure in Shumiya Cataract Rats

We attempted to prepare ophthalmic in situ gel formulations containing lanosterol (Lan) nanoparticles (LA-NPs/ISG) and investigated the characteristics, delivery pathway into the lens, and anti-cataract effects of LA-NPs/ISG using SCR-N (rats with slight lens structure collapse) and SCR-C (rats with...

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Bibliographic Details
Main Authors: Noriaki Nagai, Kazuki Umachi, Hiroko Otake, Mikako Oka, Noriko Hiramatsu, Hiroshi Sasaki, Naoki Yamamoto
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
nanoparticles
lanosterol
cataract
in situ gel
Shumiya cataract rat
Online Access:https://www.mdpi.com/1999-4923/12/7/629

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https://www.mdpi.com/1999-4923/12/7/629

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