Polymorphisms in genes involved in the NF-κB signalling pathway are associated with bone mineral density, geometry and turnover in men.

INTRODUCTION:In this study, we aimed to investigate the association between single nucleotide polymorphisms (SNPs) within two genes involved in the NF-κB cascade (GPR177 and MAP3K14) and bone mineral density (BMD) assessed at different skeletal sites, radial geometric parameters and bone turnover. M...

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Bibliographic Details
Main Authors: Delnaz Roshandel, Wendy Thomson, Stephen R Pye, Steven Boonen, Herman Borghs, Dirk Vanderschueren, Ilpo T Huhtaniemi, Judith E Adams, Kate A Ward, Gyorgy Bartfai, Felipe F Casanueva, Joseph D Finn, Gianni Forti, Aleksander Giwercman, Thang S Han, Krzysztof Kula, Michael E Lean, Neil Pendleton, Margus Punab, Frederick C Wu, Kate L Holliday, Terence W O'Neill, EMAS Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3221678?pdf=render