Differential effect of culture temperature and specific growth rate on CHO cell behavior in chemostat culture.

Differential effect of culture temperature and specific growth rate on CHO cell behavior in chemostat culture.

Mild hypothermia condition in mammalian cell culture technology has been one of the main focuses of research for the development of breeding strategies to maximize productivity of these production systems. Despite the large number of studies that show positive effects of mild hypothermia on specific...

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Bibliographic Details
Main Authors: Mauricio Vergara, Silvana Becerra, Julio Berrios, Nelson Osses, Juan Reyes, María Rodríguez-Moyá, Ramon Gonzalez, Claudia Altamirano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3974816?pdf=render

Internet

http://europepmc.org/articles/PMC3974816?pdf=render

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