Oncolytic Virus Therapy Alters the Secretome of Targeted Glioblastoma Cells

Oncolytic Virus Therapy Alters the Secretome of Targeted Glioblastoma Cells

Oncolytic virus (OV) therapy, which is being tested in clinical trials for glioblastoma, targets cancer cells, while triggering immune cells. Yet OV sensitivity varies from patient to patient. As OV therapy is regarded as an anti-tumor vaccine, by making OV-infected cancer cells secrete immunogenic...

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Bibliographic Details
Main Authors: Jakub Godlewski, Mohamed Farhath, Franz L. Ricklefs, Carmela Passaro, Klaudia Kiel, Hiroshi Nakashima, E. Antonio Chiocca, Agnieszka Bronisz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
glioblastoma
oncolytic virus
extracellular vesicles
immune response
secretome
exosomes
Online Access:https://www.mdpi.com/2072-6694/13/6/1287

Internet

https://www.mdpi.com/2072-6694/13/6/1287

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