Genetic and epigenetic alterations of the NF2 gene in sporadic vestibular schwannomas.

BACKGROUND: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identified in not only NF2-related tumors but also sporadic vestibular schwannomas (VS). This study investigated the genetic and epigenetic alterations in tumors and blood from 30 Korean patients with sporadi...

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Bibliographic Details
Main Authors: Jong Dae Lee, Tae Jun Kwon, Un-Kyung Kim, Won-Sang Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266248?pdf=render