IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection.

BACKGROUND:Single nucleotide polymorphisms (SNPs) of interleukin-28B (IL28B) have received considerable interest for their association with sustained virological response (SVR) when treating patients of genotype-1 hepatitis C virus (GT1-HCV) chronic infection with pegylated interferon and ribavirin...

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Bibliographic Details
Main Authors: Chun-Yen Lin, Ji-Yih Chen, Tsung-Nan Lin, Wen-Juei Jeng, Chien-Hao Huang, Chang-Wen Huang, Su-Wei Chang, I-Shyan Sheen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3068186?pdf=render