Clinicopathological and prognostic values of fibronectin and integrin αvβ3 expression in primary osteosarcoma

Abstract Background Osteosarcoma is a malignant bone tumor with a high potential for lung metastasis, and the prognosis for patients with metastatic disease is very poor. The interaction between fibronectin (FN) and integrin αvβ3 in soft-tissue sarcoma promotes cell migration, invasion, and lung met...

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Bibliographic Details
Main Authors: Kai Shi, Sheng-lin Wang, Bin Shen, Feng-qiang Yu, Dan-feng Weng, Jian-hua Lin
Format: Article
Language:English
Published: BMC 2019-01-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12957-019-1566-z