Clinicopathological and prognostic values of fibronectin and integrin αvβ3 expression in primary osteosarcoma
Abstract Background Osteosarcoma is a malignant bone tumor with a high potential for lung metastasis, and the prognosis for patients with metastatic disease is very poor. The interaction between fibronectin (FN) and integrin αvβ3 in soft-tissue sarcoma promotes cell migration, invasion, and lung met...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | World Journal of Surgical Oncology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12957-019-1566-z |