Cross genome phylogenetic analysis of human and <it>Drosophila</it> G protein-coupled receptors: application to functional annotation of orphan receptors

<p>Abstract</p> <p>Background</p> <p>The cell-membrane G-protein coupled receptors (GPCRs) are one of the largest known superfamilies and are the main focus of intense pharmaceutical research due to their key role in cell physiology and disease. A large number of putati...

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Bibliographic Details
Main Authors: Sowdhamini Ramanathan, Metpally Raghu
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/106