TASK-1 channels in oligodendrocytes: A role in ischemia mediated disruption

Oligodendrocytes are the myelinating cells of the CNS and, like neurons, are highly sensitive to ischemic damage. However, the mechanisms underlying cytotoxicity in oligodendrocytes during hypoxic/ischemic episodes are not fully understood. TASK-1 is a K+ leak channel that mediates hypoxic depolaris...

Full description

Bibliographic Details
Main Authors: Virginia Hawkins, Arthur Butt
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113001046