Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches.
BACKGROUND:Fasciola hepatica is the causative agent of fascioliasis, a disease affecting grazing animals, causing economic losses in global agriculture and currently being an important human zoonosis. Overuse of chemotherapeutics against fascioliasis has increased the populations of drug resistant p...
Main Authors: | Lilian Hernández Alvarez, Dany Naranjo Feliciano, Jorge Enrique Hernández González, R O Soares, Diego Enry Barreto Gomes, Pedro Geraldo Pascutti |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-05-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4433193?pdf=render |
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