Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches.

Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches.

BACKGROUND:Fasciola hepatica is the causative agent of fascioliasis, a disease affecting grazing animals, causing economic losses in global agriculture and currently being an important human zoonosis. Overuse of chemotherapeutics against fascioliasis has increased the populations of drug resistant p...

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Bibliographic Details
Main Authors: Lilian Hernández Alvarez, Dany Naranjo Feliciano, Jorge Enrique Hernández González, R O Soares, Diego Enry Barreto Gomes, Pedro Geraldo Pascutti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4433193?pdf=render

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http://europepmc.org/articles/PMC4433193?pdf=render

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