Local Drug Delivery for Prevention of Hearing Loss

Local Drug Delivery for Prevention of Hearing Loss

Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is challenging. Systemic drugs have to cross the blood-labyrinth barrier (BLB). BLB can significantly prevent effective penetration of drugs in appropriate concentrations to protect against hearing loss caus...

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Bibliographic Details
Main Authors: Leonard P. Rybak, Asmita Dhukhwa, Debashree Mukherjea, Vickram Ramkumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
intra-tympanic injection
cisplatin
noise
hearing loss
acoustic trauma
ototoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00300/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00300/full

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