Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells

Intercellular adhesion molecule 1 (ICAM-1) and the endothelial protein C receptor (EPCR) are candidate receptors for the deadly complication cerebral malaria. However, it remains unclear if Plasmodium falciparum parasites with dual binding specificity are involved in cytoadhesion or different parasi...

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Bibliographic Details
Main Authors: Marion Avril, Maria Bernabeu, Maxwell Benjamin, Andrew Jay Brazier, Joseph D. Smith
Format: Article
Language:English
Published: American Society for Microbiology 2016-07-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/4/e00615-16