Ficus carica leaves extract inhibited pancreatic β-cell apoptosis by inhibiting AMPK/JNK/caspase-3 signaling pathway and antioxidation

The aim of this study was to explore the inhibitory effects of Ficus carica leaves (FCL) extract on AMPK/JNK/caspase3 signaling pathway and antioxidation in pancreatic β-cells. H&E staining, insulin immunohistochemistry, and TUNEL methods were used to investigate the effects of FCL on pancreatic...

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Bibliographic Details
Main Authors: Yin Zhang, Yingying Li, Ping Ma, Jincheng Chen, Weiping Xie
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
FCL
JNK
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353119