CYP2J2 and EETs Protect against Oxidative Stress and Apoptosis in Vivo and in Vitro Following Lung Ischemia/Reperfusion

CYP2J2 and EETs Protect against Oxidative Stress and Apoptosis in Vivo and in Vitro Following Lung Ischemia/Reperfusion

Background: Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acids to epoxyeicosatrienoic acids (EETs). EETs exert various biological effects, including anti-inflammatory, anti-apoptotic, pro-proliferation, pro-angiogenesis, anti-oxidation, and anti-fibrosis effects. However, little...

Full description

Bibliographic Details
Main Authors: Wenshu Chen, Guanying Zheng, Shijiang Yang, Wei Ping, Xiangning Fu, Ni Zhang, Dao Wen Wang, Jianing Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Epoxyeicosatrienoic acids
Apoptosis
Cytochrome P450 epoxygenase 2J2
Lung ischemia/reperfusion injury
Oxidative stress
Online Access:http://www.karger.com/Article/FullText/362950

Internet

http://www.karger.com/Article/FullText/362950

Similar Items