Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

Abstract Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction. Conserved sequences rich in aromatic residues juxtaposed to the exter...

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Bibliographic Details
Main Authors: Igor de la Arada, Johana Torralba, Igor Tascón, Adai Colom, Iban Ubarretxena-Belandia, José L. R. Arrondo, Beatriz Apellániz, José L. Nieva
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80156-w