Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.

Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.

The highly pathogenic Old World arenavirus Lassa virus (LASV) and the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) use α-dystroglycan as a cellular receptor and enter the host cell by an unusual endocytotic pathway independent of clathrin, caveolin, dynamin, and actin. Upon intern...

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Bibliographic Details
Main Authors: Giulia Pasqual, Jillian M Rojek, Mark Masin, Jean-Yves Chatton, Stefan Kunz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3169553?pdf=render

Internet

http://europepmc.org/articles/PMC3169553?pdf=render

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