GATA1 Promotes Gemcitabine Resistance in Pancreatic Cancer through Antiapoptotic Pathway

Gemcitabine-based chemotherapy is the first-line treatment for pancreatic cancer. However, chemoresistance is a major obstacle to drug efficacy, leading to poor prognosis. Little progress has been achieved although multiple mechanisms are investigated. Therefore, effective strategies are urgently ne...

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Bibliographic Details
Main Authors: Zhenyu Chang, Yanan Zhang, Jie Liu, Chengjian Guan, Xinjin Gu, Zelong Yang, Qinong Ye, Lihua Ding, Rong Liu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2019/9474273