Emergence of Amoxicillin-Resistant Variants of Spain9V-ST156 Pneumococci Expressing Serotype 11A Correlates with Their Ability to Evade the Host Immune Response.

Emergence of Amoxicillin-Resistant Variants of Spain9V-ST156 Pneumococci Expressing Serotype 11A Correlates with Their Ability to Evade the Host Immune Response.

Capsular switching allows pre-existing clones of Streptococcus pneumoniae expressing vaccine serotypes to escape the vaccine-induced immunity by acquisition of capsular genes from pneumococci of a non-vaccine serotype. Here, we have analysed the clonal composition of 492 clinical isolates of serotyp...

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Bibliographic Details
Main Authors: Leire Aguinagalde, Bruno Corsini, Arnau Domenech, Mirian Domenech, Jordi Cámara, Carmen Ardanuy, Ernesto García, Josefina Liñares, Asunción Fenoll, Jose Yuste
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4569277?pdf=render

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http://europepmc.org/articles/PMC4569277?pdf=render

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