Complex interactions of lovastatin with 10 chemotherapeutic drugs: a rigorous evaluation of synergism and antagonism

Abstract Background Evidence bearing on the role of statins in the prevention and treatment of cancer is confounded by the diversity of statins, chemotherapeutic agents and cancer types included in the numerous published studies; consequently, the adjunctive value of statins with chemotherapy remain...

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Bibliographic Details
Main Authors: Kaitlyn A. Khandelwal Gilman, Seungmin Han, Young-Wook Won, Charles W. Putnam
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-07963-w