Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile
Shrew-1, also called AJAP1, is a transmembrane protein associated with E-cadherin-mediated adherence junctions and a putative tumor suppressor. Apart from its interaction with β-catenin and involvement in E-cadherin internalization, little structure or function information exists. Here we explored s...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2016-11-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/5/11/1607 |