RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

Keloids are disfiguring, fibroproliferative growths and their pathogenesis remains unclear, inhibiting therapeutic development. Available treatment options have limited efficacy and harbor safety concerns. Thus, there is a great need to clarify keloid pathomechanisms that may lead to novel treatment...

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Bibliographic Details
Main Authors: Jianni Wu, Ester Del Duca, Michael Espino, Alyssa Gontzes, Inna Cueto, Ning Zhang, Yeriel D. Estrada, Ana B. Pavel, James G. Krueger, Emma Guttman-Yassky
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
RNA-seq
keloids
immune
Th2
JAK3
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.597741/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.597741/full

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