Role of Chromodomain-Helicase-DNA-Binding Protein 4 (CHD4) in Breast Cancer

Role of Chromodomain-Helicase-DNA-Binding Protein 4 (CHD4) in Breast Cancer

Chromodomain-helicase-DNA-binding protein 4 (CHD4) is an epigenetic regulator identified as an oncogenic element that may provide a novel therapeutic target for the treatment of breast cancer (BC). CHD4—the core component of the nucleosome remodeling and deacetylase (NuRD) complex—may be mutated in...

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Bibliographic Details
Main Authors: Apolonia Novillo, Ana Fernández-Santander, Maria Gaibar, Miguel Galán, Alicia Romero-Lorca, Fadoua El Abdellaoui-Soussi, Pablo Gómez-del Arco
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
breast cancer
CHD4 gene
mutation
therapies in breast cancer
chromatin remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.633233/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.633233/full

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