Molecular modeling and analysis of the 3D pharmacophore structure of the selective PI3K-α inhibitors as antitumor agents
The importance of the activation of phosphatidylinositol-3-kinase (PI3K) in the processes of tumor cell formation and growth has brought great interest in the development of new antitumor drugs that inhibit the PI3K-Akt signaling pathway. Recent studies have shown that in most tumors the activity of...
Main Authors: | , , , |
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Format: | Article |
Language: | srp |
Published: |
Pharmaceutical Association of Serbia, Belgrade, Serbia
2018-01-01
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Series: | Arhiv za farmaciju |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2018/0004-19631804860J.pdf |