Molecular modeling and analysis of the 3D pharmacophore structure of the selective PI3K-α inhibitors as antitumor agents

The importance of the activation of phosphatidylinositol-3-kinase (PI3K) in the processes of tumor cell formation and growth has brought great interest in the development of new antitumor drugs that inhibit the PI3K-Akt signaling pathway. Recent studies have shown that in most tumors the activity of...

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Bibliographic Details
Main Authors: Jovanović Milan, Nikolić Katarina, Gagić Žarko, Agbaba Danica
Format: Article
Language:srp
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia 2018-01-01
Series:Arhiv za farmaciju
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2018/0004-19631804860J.pdf