Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic

Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic

In this study, we analyzed full-length SARS-CoV-2 genomes from multiple countries to determine early trends in the evolutionary dynamics of the novel COVID-19 pandemic. Results indicated SARS-CoV-2 evolved early into at least three phylogenetic groups, characterized by positive selection at specific...

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Bibliographic Details
Main Authors: Lauro Velazquez-Salinas, Selene Zarate, Samantha Eberl, Douglas P. Gladue, Isabel Novella, Manuel V. Borca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
evolution
epistasis
positive selection
COVID-19
SARS-CoV2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.550674/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.550674/full

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