A Practical Guide to Rodent Islet Isolation and Assessment Revisited

A Practical Guide to Rodent Islet Isolation and Assessment Revisited

Abstract Insufficient insulin secretion is a key component of both type 1 and type 2 diabetes. Since insulin is released by the islets of Langerhans, obtaining viable and functional islets is critical for research and transplantation. The effective and efficient isolation of these small islands of e...

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Bibliographic Details
Main Authors: Kathryn L. Corbin, Hannah L. West, Samantha Brodsky, Nicholas B. Whitticar, William J. Koch, Craig S. Nunemaker
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Biological Procedures Online
Subjects:
Islets of Langerhans
Isolation
Beta cell
Collagenase
Density gradient
Neonatal
Online Access:https://doi.org/10.1186/s12575-021-00143-x

Internet

https://doi.org/10.1186/s12575-021-00143-x

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