TRPA1 Ion Channel Determines Beneficial and Detrimental Effects of GYY4137 in Murine Serum-Transfer Arthritis

TRPA1 Ion Channel Determines Beneficial and Detrimental Effects of GYY4137 in Murine Serum-Transfer Arthritis

Modulation of nociception and inflammation by sulfide in rheumatoid arthritis and activation of transient receptor potential ankyrin 1 (TRPA1) ion channels by sulfide compounds are well documented. The present study aims to investigate TRPA1-mediated effects of sulfide donor GYY4137 in K/BxN serum-t...

Full description

Bibliographic Details
Main Authors: István Z. Bátai, Cecília Pápainé Sár, Ádám Horváth, Éva Borbély, Kata Bölcskei, Ágnes Kemény, Zoltán Sándor, Balázs Nemes, Zsuzsanna Helyes, Anikó Perkecz, Attila Mócsai, Gábor Pozsgai, Erika Pintér
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
GYY4137
TRPA1
K/BxN serum-transfer model
arthritis
hydrogen sulphide
polysulfide
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00964/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00964/full

Similar Items