Two-hit Hypothesis and Multiple Organ Dysfunction Syndrome

A severe insult in the form of infection or trauma primes the host immune system so that a subsequent, relatively trivial insult produces a markedly exaggerated host immune response, which can lead to multiple organ dysfunction syndrome (MODS) and death. This forms the basis of the “two-hit hypothe...

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Bibliographic Details
Main Authors: I Butt, Badri Man Shrestha
Format: Article
Language:English
Published: Nepal Medical Association 2008-04-01
Series:Journal of Nepal Medical Association
Online Access:http://jnma.com.np/jnma/index.php/jnma/article/view/318