Two-hit Hypothesis and Multiple Organ Dysfunction Syndrome
A severe insult in the form of infection or trauma primes the host immune system so that a subsequent, relatively trivial insult produces a markedly exaggerated host immune response, which can lead to multiple organ dysfunction syndrome (MODS) and death. This forms the basis of the “two-hit hypothe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nepal Medical Association
2008-04-01
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Series: | Journal of Nepal Medical Association |
Online Access: | http://jnma.com.np/jnma/index.php/jnma/article/view/318 |