Intrapatient Variability in Tacrolimus Trough Levels Over 2 Years Affects Long-Term Allograft Outcomes of Kidney Transplantation

Intrapatient Variability in Tacrolimus Trough Levels Over 2 Years Affects Long-Term Allograft Outcomes of Kidney Transplantation

This study aimed to determine the impact of tacrolimus (TAC) trough level (C0) intrapatient variability (IPV) over a period of 2 years after kidney transplantation (KT) on allograft outcomes. In total, 1,143 patients with low immunologic risk were enrolled. The time-weighted coefficient variability...

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Bibliographic Details
Main Authors: Yohan Park, Hanbi Lee, Sang Hun Eum, Hyung Duk Kim, Eun Jeong Ko, Chul Woo Yang, Byung Ha Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
allograft
rejection
transplant
graft survival
tacrolimus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.746013/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.746013/full

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