Thermal latency studies in opiate-treated mice

Background: The change in the reaction time of a tail or paw exposed to a thermal stimulus is a measure of nociceptive activity in laboratory animals. Tail-flick and plantar thermal sensitivity (Hargreaves) tests are non-invasive, minimize stress, and can be used to screen animals for phenotype and...

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Bibliographic Details
Main Authors: Noam Schildhaus, Eliana Trink, Chirs Polson, Louis DeTolla, Betty M Tyler, George I Jallo, Sino Tok, Michael Guarnieri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2014;volume=6;issue=1;spage=43;epage=47;aulast=Schildhaus