Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes

Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes

The precise control of cytokine production by innate lymphoid cells (ILCs) and their T cell adaptive system counterparts is critical to mounting a proper host defense immune response without inducing collateral damage and autoimmunity. Unlike T cells that differentiate into functionally divergent su...

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Bibliographic Details
Main Authors: Nilisha Fernando, Giuseppe Sciumè, John J. O’Shea, Han-Yu Shih
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
signal-regulated transcription factors
lineage-determining transcription factors
de novo enhancers
poised enhancers
ATAC-seq and chromatin accessibility
innate lymphoid cell (ILC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.655590/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.655590/full

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