Optimization of Enzymatic Synthesis of Oleoyl-Diethanolamide in Solvent-Free System

Oleoyl-diethanolamide was synthesized through amidification of diethanolamine (DEA) with oleic acid (OA) using immobile lipase as a biocatalyst. Response Surface Methodology (RSM) based on five-level five variable, Central Composite Rotatable Design (CCRD) was developed to study and to optimize the...

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Bibliographic Details
Main Authors: Zuhrina Masyithah, Tjahjono Herawan
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2017-09-01
Series:Journal of Pure and Applied Microbiology
Subjects:
Online Access:https://microbiologyjournal.org/optimization-of-enzymatic-synthesis-of-oleoyl-diethanolamide-in-solvent-free-system/