Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity

Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity

Apolipoprotein E (ApoE) has become a primary focus of research after the discovery of its strong linkage to Alzheimer’s disease (AD), where the ApoE4 variant is the highest genetic risk factor for this disease. ApoE is commonly found in amyloid deposits of different origins, and its intera...

Full description

Bibliographic Details
Main Authors: Anna L. Gharibyan, Tohidul Islam, Nina Pettersson, Solmaz A. Golchin, Johanna Lundgren, Gabriella Johansson, Mélany Genot, Nina Schultz, Malin Wennström, Anders Olofsson
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomolecules
Subjects:
apolipoprotein e
iapp amyloid
thioflavin t
pericytes
cytotoxicity
Online Access:https://www.mdpi.com/2218-273X/10/1/134

Internet

https://www.mdpi.com/2218-273X/10/1/134

Similar Items