Using Serial Analysis of Gene Expression to Identify Tumor Markers and Antigens

Tumor markers and antigens are normally highly expressed in malignant tissue, but not in the surrounding normal tissue. Serial Analysis of Gene Expression (SAGE) is a technology that counts mRNA transcripts and can be used to find those genes most highly induced in malignant tissues. SAGE produces a...

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Bibliographic Details
Main Author: Gregory J. Riggins
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2001/185929