An Overview of Bortezomib-Induced Neurotoxicity
The boronic acid dipeptide bortezomib, able to induce tumor cell death by degradation of key proteins, is the first proteasome inhibitor drug to enter clinical practice. It is employed as first-line treatment in relapsed or resistant multiple myeloma (MM) patients. However, bortezomib often induces...
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Format: | Article |
Language: | English |
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MDPI AG
2015-07-01
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Series: | Toxics |
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Online Access: | http://www.mdpi.com/2305-6304/3/3/294 |