An Overview of Bortezomib-Induced Neurotoxicity

The boronic acid dipeptide bortezomib, able to induce tumor cell death by degradation of key proteins, is the first proteasome inhibitor drug to enter clinical practice. It is employed as first-line treatment in relapsed or resistant multiple myeloma (MM) patients. However, bortezomib often induces...

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Bibliographic Details
Main Author: Cristina Meregalli
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Toxics
Subjects:
Online Access:http://www.mdpi.com/2305-6304/3/3/294