Controlling DNA-end resection: a new task for CDKs

Controlling DNA-end resection: a new task for CDKs

DNA double-strand breaks (DSBs) are repaired by two major pathways: homologous recombination (HR) and nonhomologous end-joining (NHEJ). The choice between HR and NHEJ is highly regulated during the cell cycle. DNA-end resection, an evolutionarily conserved process that generates long stretches of si...

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Bibliographic Details
Main Authors:	Lorenza P Ferretti, Lorenzo eLafranchi, Alessandro A Sartori
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-06-01
Series:	Frontiers in Genetics
Subjects:	Homologous Recombination Phosphorylation Pin1 cyclin-dependent kinase DNA double-strand break repair DNA-end resection
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00099/full

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