Controlling DNA-end resection: a new task for CDKs
DNA double-strand breaks (DSBs) are repaired by two major pathways: homologous recombination (HR) and nonhomologous end-joining (NHEJ). The choice between HR and NHEJ is highly regulated during the cell cycle. DNA-end resection, an evolutionarily conserved process that generates long stretches of si...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-06-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00099/full |