Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction

Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction

CX3CL1, which is a chemokine involved in many aspects of human pregnancy, is a membrane-bound chemokine shed into circulation as a soluble isoform. Placental CX3CL1 is induced by inflammatory cytokines and is upregulated in severe early-onset preeclampsia. In this study, the hypothesis was addressed...

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Bibliographic Details
Main Authors: Olivia Nonn, Jacqueline Güttler, Désirée Forstner, Sabine Maninger, Julianna Zadora, András Balogh, Alina Frolova, Andreas Glasner, Florian Herse, Martin Gauster
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
first trimester pregnancy
placenta
angiotensin
CX3CL1
inflammation
Online Access:https://www.mdpi.com/1422-0067/20/3/641

Internet

https://www.mdpi.com/1422-0067/20/3/641

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