Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

Suliman Al-Fayoumi,1 Taishi Hashiguchi,2 Yuka Shirakata,2 John Mascarenhas,3 Jack W Singer1 1CTI BioPharma, Seattle, WA, USA; 2SMC Laboratories, Tokyo, Japan; 3Tish Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA Background: Fibrotic diseases result from an exuberant res...

Full description

Bibliographic Details
Main Authors: Al-Fayoumi S, Hashiguchi T, Shirakata Y, Mascarenhas J, Singer JW
Format: Article
Language:English
Published: Dove Medical Press 2018-05-01
Series:Journal of Experimental Pharmacology
Subjects:
janus kinase 2
interleukin-1 receptor-associated kinase 1
colony-stimulating factor 1 receptor kinase
steatosis
myelofibrosis
liver fibrosis
Online Access:https://www.dovepress.com/pilot-study-of-the-antifibrotic-effects-of-the-multikinase-inhibitor-p-peer-reviewed-fulltext-article-JEP

Internet

https://www.dovepress.com/pilot-study-of-the-antifibrotic-effects-of-the-multikinase-inhibitor-p-peer-reviewed-fulltext-article-JEP

Similar Items