Prognostic value of CD73 expression in resected colorectal cancer liver metastasis

Prognostic value of CD73 expression in resected colorectal cancer liver metastasis

Immune checkpoint blockade has not yet been effective in patients with mismatch repair proficient metastatic colorectal cancer. Targeting immunosuppressive metabolic pathways is being explored as a new immunotherapeutic approach. We assessed whether CD73, the rate limiting enzyme that catalyzes the...

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Bibliographic Details
Main Authors: Nouredin Messaoudi, Isabelle Cousineau, Elizabeth Arslanian, David Henault, David Stephen, Franck Vandenbroucke-Menu, Michel Dagenais, Richard Létourneau, Marylène Plasse, André Roy, Réal Lapointe, Dirk Ysebaert, Dominique Trudel, Geneviève Soucy, John Stagg, Simon Turcotte
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
cd73-adenosine pathway
biomarker
colorectal cancer
immune checkpoint
liver metastasis
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1746138

Internet

http://dx.doi.org/10.1080/2162402X.2020.1746138

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